Below are the 5 most recent journal entries recorded in modafinilinfo's InsaneJournal:

Friday, October 7th, 2011
8:27 pm	The Modafinil Order for Narcolepsy Why is there a noted increase for modafinil order? It is because more and more people are suffering from narcolepsy. Narcolepsy affects the central nervous system. The chief complaint of a person experiencing narcolepsy would be excessive daytime sleepiness. A person would also experience loss of muscle tone, hypnagogic hallucinations and the inability to move or talk. Initially, narcolepsy happens during adolescent stage. It both equally affects women and men. Initial symptom to show would be excessive daytime sleepiness. Most people don’t recognize it because it gradually progresses over time. Other symptoms will follow in months or years. One may not consider having a modafinil order at these times because the symptoms are not severe. Occurrence of narcolepsy One might wonder as to how common narcolepsy is. The occurrence rate of narcolepsy is the same as that of Parkinson’s disease and multiple sclerosis. According to the National Institute of Neurological Disorders and Stroke, one in every 2,000 people suffers from narcolepsy. According to the American Sleep Association’s statistics, about 125,000 to 200,000 Americans are narcoleptic. However, less than 50,000 are diagnosed by a sleep medicine specialist. Not many individuals seek medical attention not unless it becomes severe. Cause of narcolepsy Latest discoveries reveal that narcolepsy is due to the abnormalities in the structure and function of hypocretin neurons. These nerve cells are detected in patients with narcolepsy and can be found in the hypothalamus. Also, narcolepsy is also linked to a certain human leukocyte antigen. They are the ones that genetically figure out the proteins found in your white blood cells. The linkage of the human leukocyte antigen led to the possibility that narcolepsy is an autoimmune disease. It’s similar to multiple sclerosis and ankylosing spondylitis. Signs and symptoms of narcolepsy Excessive daytime sleepiness is one of the major symptoms of narcolepsy. It takes more than just a modafinil order to treat this symptom. Excessive daytime sleepiness could lead to situations like falling asleep during eating a meal or while watching TV. Moreover, it could happen at inappropriate times. A person may also feel sleepy, tired, lazy, low on energy and fatigued. The symptom could go on the entire day and irresistible urge to sleep attacks. Cataplexy would mean that a person will have a sudden temporary muscle weakness. It is triggered by certain emotions like excitement, surprise, anger or laughter. Factors that trigger cataplexy would include stress, physical fatigue and sleepiness. Hypnagogic hallucinations are dream-like situations that happen during the transition from being awake to sleep. It may involve your sense of hearing, sight, touch and balance. It will mix images of your environment to dream-like images. Sleep paralysis is another symptom of narcolepsy. You will be unable to move or talk during the sleep-wake transition. It may last for seconds or minutes. It can occur together with your hypnagogic hallucinations. Some might be frightened of this stage because of the scary sensation of not being able to breathe. The three symptoms namely cataplexy, hypnagogic hallucinations and sleep paralysis are coined as the REM related abnormalities. (Comment on this)
8:24 pm	Modafinil Order for People with Narcolepsy There is an increase in modafinil order because there’s a noted increase in the number of people suffering from narcolepsy. Three million individuals around the world are affected by narcolepsy. From what most people know, narcolepsy is a chronic sleep disorder wherein one has the extreme urge to sleep at any given time. It can happen during work, driving, talking to a friend or even while eating. It occurs during inappropriate times and some people could not fight such urge. In return, a person experiences disrupted night sleep and excessive daytime sleepiness. Usually, a narcoleptic will enter the REM stage of sleep within the span of 10 minutes. A normal person would enter the REM stage after 90 minutes into the sleep. Narcoleptics do not only suffer from extreme urge to sleep at inappropriate times. They also suffer from cataplexy. Such condition could trigger the muscles to develop sudden weakness because of strong emotions. However, not all people have cataplexy when emotionally triggered. The muscle weakness will begin to manifest in the facial muscles. There’s a dropping of the jaw or head then it leads to knee weakness. A person collapsing is possible. People with cataplexy will also having impaired vision and slurred speech. On the brighter side, hearing and awareness are not affected. Narcolepsy is a neurological disorder that can be treated when there is a modafinil order. It is not brought about by any psychological or mental disease. It may be due to genetic abnormalities and other biologic factors affecting the brain. A narcoleptic person is most likely to feel sleepy during daytime. Naps can happen frequently in the day and it is physically irresistible. There’s a tetrad symptoms of narcolepsy. These would be cataplexy, sleep paralysis and hypnagogic hallucinations. The person will remain conscious at all times but a temporary sleep paralysis will occur. Automatic behavior will immediately occur after the episode. It means that a person will go back to his normal behavior, resuming all activities he left behind. A person suffering from the symptoms of narcolepsy will undergo several diagnostic exams like multiple sleep latency test and polysomnogram. Both diagnostic exams are facilitated by a sleep medicine specialist. When it comes to the multiple sleep latency test, one is asked to sleep every 2 hours during normal waking hours. Each stage of sleep is monitored by the sleep specialist. This test is to assess the level of excessive sleepiness and how fast REM sleep starts. The treatment will vary from one person to another. The modafinil order is tailored to the individual depending on the presenting symptoms and therapeutic response. Modafinil order requests will be frequent in order to achieve the optimal control of symptoms. Besides modafinil, non-stimulant drugs could also be prescribed such as atomoxetine and norepinephrine reuptake inhibitors. To treat cataplexy, it should be treated with tricyclic antidepressants like clomipramine or protriptyline. These drugs could also treat other REM-sleep symptoms. Lifestyle changes are also recommended. One should reduce stress and include exercise regimen in his daily activities. Coffee and nicotine intake should also be decreased. (Comment on this)
8:21 pm	Information You Need About Provigil Generic First and foremost, you need to know that Provigil generic is not the same as modafinil. Modafinil is the active component found in Provigil. People mistakenly consider that the active ingredient as the generic name. Hence, the generic name it has is not similar with generic version of the drug. When Provigil generic is taken with other drugs, it may result to negative interactions. Some of these drugs are listed below. 1. There’s a negative effect in some cyclosporines such as Gengraf, Neoral and Sandimmune when taken with Provigil. It lowers the level of cyclosporine in the blood making the cyclosporine less effective. If both drugs are needed to be taken, consult your physician. He might increase the dosage of cyclosporine as needed. 2. There are some antibiotics and antifungals that can promote higher doses of Provigil generic. Inform your doctor right away that you are under an antibiotic/antifungal treatment so he can give you a lower Provigil generic. 3. Diazepam and Provigil generic can increase the levels of diazepam in the blood. Hence, a person will experience severe side effects such as fever, headache, gastric upset, dizziness and numbness. 4. Women who are under the hormonal replacement therapy should inform their doctor before taking Provigil. Also, people using estrogen-containing contraceptives need to know that their birth control will not be 100% effective if taken with Provigil. Such estrogen-containing contraceptives include birth control pills, IUD, patches and rings. 5. Drugs similar to Provigil give a dangerous effect when taken together with monoamine oxidase inhibitors. Although, it has not been proven that taking Provigil generic is dangerous if taken with a monoamine oxidase inhibitor. Try to avoid taking it together as much as possible until further studies have been made. 6. Propanolol and Provigil taken together results to an increase of propranolol in the blood. It will increase the possibility for you to experience some side effects. Once again, always consult your doctor before taking the two drugs together. 7.Rifamycin antibiotics can lower down the level of Provigil in your blood. Provigil will become less effective so don’t start rifamycin antibiotics without informing your doctor. He may have to increase the dosage or frequency of your modification. 8. Benzodiazepine can decrease the level of Provigil in your blood. Be sure to check with your healthcare worker if it is okay to combine these two drugs. Because Provigil can increase the level of benzodiazepine in your blood. 9. Protease inhibitors have drug interactions with Provigil. However, not all protease inhibitors have negative effects when combined with Provigil. 10. When tricyclic antidepressants and Provigil are combined together will elevate the level of tricyclic antidepressant in the blood. 11. Warfarin such as Coumadin and Jantoven are blood thinners. These blood thinners can interact with Provigil. A person needs to be monitored by a healthcare worker when taking these drugs together. These are some drugs that have an interaction with Provigil. It’s best if you inform your healthcare provider all the drugs you are taking so that certain interventions will be done. (Comment on this)
8:18 pm	Provigil Generic For Obstructive Sleep Apnea Obstructive sleep apnea is a disease which partially or totally blocks the flow of air as you breathe while you are sleeping. The airway becomes constricted, blocked or limp. The momentary halt in breathing is coined as an apnea episode. When there’s a decrease in airflow, it becomes a hypopnea episode. Brief apnea episodes while sleeping is a common occurrence. Long pauses would be a medical concern. Cause of Obstructive Sleep Apnea When you are asleep, all your muscles are more relaxed. This would mean that the muscles that keep your airway open are more relaxed. Hence, the muscles that allow air to flow into your lungs are affected too. The upper throat will remain open while you are asleep so air can pass by. Unfortunately, not everyone have a wide throat area. The muscles in your upper throat relax your breathing stops for about 10 seconds so it’s coined as apnea. A person with obstructive sleep apnea will snore because the air is trying to squeeze in through the narrow airway. Other factors that increase the risk of sleep apnea would include a shorter lower jaw than the upper jaw, certain shape of the palate, large tonsils, obesity and a large tongue that falls back and blocks the airway. Before deciding on buying Provigil generic as a treatment, you should know the symptoms. It’s hard to tell because a person with obstructive sleep apnea is not aware of the apnea episodes during sleep. The one lying beside the person with sleep apnea is the only one who can witness the episodes of apnea. A person will also snore loudly and it is interfered with a long silent period with no breathing. It is then followed by a loud snort and gasp because a person is trying to breathe. This kind of pattern will repeat over and over again not unless it is treated with Provigil generic. Such symptoms will leave the person not refreshed and wanting sleep throughout the day. The sleep apnea will make the person grumpy, patient, irritable and forgetful. There’s a bigger chance that the person will fall asleep while working or doing something important like driving. The attention span, focus and alertness become less. Furthermore, excessive sleepiness will lead to depression, leg swelling, psychosis and cardiovascular diseases. When it comes to the treatment, the goal should be towards keeping the airway open and maintaining alertness. You might want to decide some lifestyle modification like limiting the alcohol intake, losing weight and having good sleep hygiene. In some cases, surgery is advised. One has to undergo uvulopalatopharyngoplasty which is the removal of extra tissue at the back of the throat. For the excessive sleepiness, you can take Provigil generic. It has to be prescribed by your physician. Provigil generic balances the neurotransmitters in your brain responsible for the sleep/wake pattern. Take the treatment of sleep apnea seriously. Poorly treated sleep apnea could increase the anxiety and depression of a person. There’s a decreased interest in sex as well. (Comment on this)
8:08 pm	Buy Modafinil To Treat Some Sleep Disorders When you buy modafinil, it’s going to treat some sleep disorders. However, it doesn’t cure you from certain sleep disorders. Let’s tackle on some sleep orders before you buy modafinil. It’s always best to get equipped with information. When one will buy modafinil, it means that he may be experiencing excessive sleepiness. Excessive sleepiness is just a symptom of an underlying disease that’s related to sleep deprivation. One may experience excessive daytime sleepiness when he has narcolepsy, obstructive sleep apnea or shift work sleep disorder. What’s worse is that, sleep excessiveness is the chief complaint of most people with psychiatric illness. Before treating an individual with excessive sleepiness by suggesting the person to buy modafinil, an accurate diagnosis should be done. It begins with a detailed assessment with the use of several questionnaires. Such questionnaires will determine the possible factors that could contribute to the extreme sleepiness. Sleep studies are to be done as well. It should include the multiple sleep latency tests, maintenance of wakefulness test wherein both tests should be done in a sleep laboratory. However, the Epworth Sleepiness Scale is the suggestive exam. It’s a basic assessment that measures the person’s level of sleepiness. A person will be tested for his likelihood to fall asleep in eight different circumstances. A physical assessment is also needed. It’s important to determine whether the person is obese or is suffering from systemic hypertension. These two conditions is link with sleep-disordered breathing. People who have more than 20-40% body mass index are most likely to suffer from obstructive sleep apnea. Other predisposing factors of obstructive sleep apnea includes higher apnea, male sex, older age, elevated fasting sugar and observed apneas. What is more is that, people with lower jaw structure and lesser neck circumference are more prone to excessive sleepiness. Nevertheless, polysomnography is necessary. It is a test to determine the sleep disordered breathing and assesses for any irregular movements during sleep. If the tests prove that the degree of your excessive sleepiness is severe, treatment should be given immediately. Initially, people with obstructive sleep apnea need to continue their nasal continuous positive airway pressure. A strict diet plan and exercise regimen is important to help a person lose weight. Other non-pharmacologic treatments suggest the intake of iron supplements, improved sleep hygiene, reduce intake of alcohol, caffeine and nicotine. Naps would also be helpful. As much as possible, watching television and sexual activity should be done outside the bedroom. And return to your bed only when you are sleepy. There’s no point in staying in bed when you are unable to fall asleep after 30 minutes. When non-pharmacologic treatments fail, buy modafinil. It can reduce the occurrence of residual sleepiness for patients with obstructed sleep apnea. It’s a somnolytic agent that can treat shift work sleep disorder and narcolepsy. Sympathomimetic agents can be given as early treatments. The intake of amphetamines can increase the level of alertness of a person. Sodium oxybate can also be given for patients with cataplexy associated with narcolepsy. In a way, it regulates your sleep architecture. (Comment on this)